Hacking COVID-19: Metabolic Pathway Analysis Yields SARS-CoV-2 Drug Targets (Coursera)

The course will begin by discussing motivations for Pathway Bioinformatics, and by presenting an overview of metabolism and of metabolic pathways. Next it will discuss machine representation of pathway data, and methods for pathway visualization. The course will describe how the metabolic pathways of an organism can be inferred from genome data, and how pathways can be used to interpret high-throughput data such as transcriptomics data. It will show how to predict the essential genes of an organism via reachability analysis, and then present a metabolic analysis of human metabolism when interacting with SARS-CoV-2 to predict SARS-CoV-2 drug targets.

Syllabus

WEEK 1

Hacking COVID-19 — Course 4: Searching for Drug Targets

In this course, we will use pathway bioinformatics techniques to search for potential COVID-19 drug targets.