Oct 24th 2016

Clinical Kidney Transplantation (Coursera)

Kidney transplantation is a major advance of modern medicine which provides high-quality of life for patients with end-stage renal disease. What used to be an experimental, risky, and very limited treatment option more than 50 years ago is now routinely performed in many countries worldwide. The number of renal transplants is expected to rise sharply in the next decade since the proportion of patients with end stage renal disease is increasing.

Are you interested in clinical kidney, pancreas and islet transplantation? If you are a (bio) medical student or a health care professional who works in the (pre) clinical transplant field this might be the course for you. This course is also for anyone interested in the research and knowledge on clinical transplantation. The course will be taught by a multidisciplinary team of transplant professionals and will give you the state of the art updates.

It is divided in 4 modules:

1) Before the transplant

2) The surgical procedures and the challenged patient, including the patient with diabetes

3) Early challenges

4) Late challenges after transplantation.

The offered modules will include lectures, interactive patient cases, 3D movies, interviews with well-known experts and with patients and a donor, a serious game to increase knowledge of the field and of course an active forum. Become an expert and join us!

The course is endorsed by The European Society of Organ Transplantation (ESOT), The International Society of Nephrology (ISN) and The Transplantation Society (TTS).

Who is this class for:

Anyone with a general interest in Clinical Kidney Transplantation, both beginners and professionals. This course is free, and will remain free for participants. You can purchase a certificate.



Welcome to the course

In this course you will learn about clinical kidney, pancreas and islet transplantation and its challenges. Before the Transplant

We will answer important questions before transplantation. These include: why is transplantation the preferred option for patients with end stage renal disease? what are the immunological barriers for transplantation? and what are the selection criteria before transplantation? Unique 3d movies about the different immunological tests will help you to understand the concepts. There are also advanced optional lectures, including a fascinating movie about the Eurotransplant allocation system. At the end of the module we will link the contents you have learned to clinical patient cases, patient - donor interviews and a quiz.

Graded: Check your knowledge


The Procedure and the Patient

Now you know the factors of importance before transplantation, including the immunological barriers and important aspects for patient selection, we can focus on challenged patient groups and on surgical procedures. What does a kidney, pancreas and islet transplantation surgical procedure look like? What is important? And what are the key aspects in elderly patients, patients with diabetes and immunological challenged patients. We have unique visulisations and a game about a patient case. Advanced readings will invite you to look at the different subjects in more depth. At the end of the module there are interviews about a patient with diabetes and the transplant recipient and donor to illustrate the impact of life. You can discuss patient cases on the forum together with your peers.

Graded: Check your knowledge


Early Challenges in Transplantation

You are now familiar with the basic knowledge about challenges in transplant recipients and the surgical transplant procedures. Once the transplantation has been successful, it doesn’t mean everything is stable. What are actually the graft survival data? Which challenges do we face in the first months? How can we tackle these challenges? 3D movies about early surgical challenges and about the targets for immunosuppressives, including cell therapy, will help you to understand the concepts. In addition, we invite you to master the advanced knowledge and to give your opinion in the patient cases in the forum. There is also a serious game about a patient case. Can you solve the challenges? And can you think of a scenario for the game and help us building? We will make a game of the best scenario, which will be incorporated in the course.

Graded: Check your knowledge


Late Challenges in Transplantation

Now you’ve learned about the challenges in the early period after transplantation. But what about the late period? What is the long term patient and allograft survival? Have we improved in the last decades. What are the main causes for morbidity and mortality? And can we reach tolerance in the future? We invite you to give your opinion in the patient cases and to discuss it on the forum. There are also advanced readings to look at additional subjects, including recurrence of the kidney disease after transplantation, the organization of dermatological care for the transplant recipiënt and the role of the patient himself in the whole process. The interview about tolerance gives you insight why pregnancy is of interest to understand the concept of tolerance and which steps have been made from lab research to a clinical protocol.

Graded: Check your knowledge

Graded: Final Exam