Learn to use tools from the Bioconductor project to perform analysis of genomic data. This is the fifth course in the Genomic Big Data Specialization from Johns Hopkins University.
Data analysis has replaced data acquisition as the bottleneck to evidence-based decision making --- we are drowning in it. Extracting knowledge from large, heterogeneous, and noisy datasets requires not only powerful computing resources, but the programming abstractions to use them effectively. The abstractions that emerged in the last decade blend ideas from parallel databases, distributed systems, and programming languages to create a new class of scalable data analytics platforms that form the foundation for data science at realistic scales.
In this course, you will learn the landscape of relevant systems, the principles on which they rely, their tradeoffs, and how to evaluate their utility against your requirements. You will learn how practical systems were derived from the frontier of research in computer science and what systems are coming on the horizon. Cloud computing, SQL and NoSQL databases, MapReduce and the ecosystem it spawned, Spark and its contemporaries, and specialized systems for graphs and arrays will be covered.
You will also learn the history and context of data science, the skills, challenges, and methodologies the term implies, and how to structure a data science project. At the end of this course, you will be able to:
1. Describe common patterns, challenges, and approaches associated with data science projects, and what makes them different from projects in related fields.
2. Identify and use the programming models associated with scalable data manipulation, including relational algebra, mapreduce, and other data flow models.
3. Use database technology adapted for large-scale analytics, including the concepts driving parallel databases, parallel query processing, and in-database analytics
4. Evaluate key-value stores and NoSQL systems, describe their tradeoffs with comparable systems, the details of important examples in the space, and future trends.
5. “Think” in MapReduce to effectively write algorithms for systems including Hadoop and Spark. You will understand their limitations, design details, their relationship to databases, and their associated ecosystem of algorithms, extensions, and languages. write programs in Spark
6. Describe the landscape of specialized Big Data systems for graphs, arrays, and streams
Data Manipulation at Scale: Systems and Algorithms is course 1 of 4 in the Data Science at Scale Specialisation.
This Specialization covers intermediate topics in data science. You will gain hands-on experience with scalable SQL and NoSQL data management solutions, data mining algorithms, and practical statistical and machine learning concepts. You will also learn to visualize data and communicate results, and you’ll explore legal and ethical issues that arise in working with big data. In the final Capstone Project, developed in partnership with the digital internship platform Coursolve, you’ll apply your new skills to a real-world data science project.