Drug Discovery

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Innovate & Regulate: Drug Research, Costs, Clinical Trials & Approval (edX)

At some point in their life, essentially everyone needs to use medication for some type of disease treatment or cure. While medications offer great benefits, the cost of drugs, especially new drugs, and the lack of treatment for some diseases can raise questions about business activity behind the creation [...]

Measuring Pharmacodynamics: From Ligand Binding to Clinical Outcomes (edX)

Drugs are biologically active compounds. Drug discovery and drug development rely on methods for measuring biological activity. The term “activity” is quite general. In practice, a substance’s biological activity can refer to how a substance affects a biological pathway, cell-level responses, safety risks, how long a substance resides within [...]

Literature Case Studies in Drug Discovery (edX)

Once a person understands the ideas of drug efficacy, potency, pharmacokinetics, and safety, original research articles can be readily understood. The Journal of Medicinal Chemistry of the American Chemical Society regularly publishes a series of articles called Drug Annotations. These articles summaries a drug discovery program from a pharmaceutical [...]