How can healthcare professionals help patients to improve their health through medicines adherence? It is estimated that 30-50% of patients do not take their medicines as prescribed. So how should we, as healthcare professionals, respond? As medicines are key to the successful management of chronic conditions, underuse or non-adherence represents a lost opportunity for the health improvement for the patient as well as being a waste of valuable resources for healthcare systems. In Europe alone, the cost of poor adherence to treatment is estimated at 195,000 lives and €20 billion annually.