Jean-Marc Cavaillon

Jean-Marc Cavaillon got his Doctorat-ès-Sciences in 1980 (University of Paris VI). After completing his post-doctoral fellowship at the University of Toronto, he joined the Institut Pasteur (Paris). He is now professor and Head of the research Unit "Cytokines & Inflammation".

At Institut Pasteur, he has been Director of the "General Immunology Course" (1997-2002), Scientific Director of the "Euroconferences" (2002-2006), and director of the Department "Infection and Epidemiology" (2006-2009). He has chaired the committee of evaluation of the scientists of the Institut (2012-2015).

Jean-Marc Cavaillon’s researches focus on inflammation and innate immunity, particularly on cytokines, bacterial endotoxins and other Toll-like receptors agonists, endotoxin tolerance, activation of monocytes/macrophages, neutrophils and more recently NK cells. He has contributed to define the altered immune status in sepsis patients and in patients with systemic inflammatory response syndrome (SIRS), and contributed to define the reprogramming of circulating leukocytes of sepsis and SIRS patients.

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Innate Immunity (FUN)

More than a century ago, Elie Metchnikoff established the bases of cellular innate immunity when he discovered the mechanism of phagocytosis. However, during most of the XXth century, adaptive immunity (also known as specific immunity) focused most of the interest of the researchers, until Charles Janeway and Polly Matzinger [...]
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