Rafael Irizarry

Dr. Irizarry received his bachelor’s in mathematics in 1993 from the University of Puerto Rico and his Ph.D. in statistics in 1998 from the University of California, Berkeley. He joined the faculty of the Department of Biostatistics in the Bloomberg School of Public Health in 1998 and was promoted to Professor in 2007. He is now Professor of Biostatistics and Computational Biology at the Dana Farber Cancer Institute and a Professor of Biostatistics at Harvard School of Public Health. Dr. Irizarry has worked on the analysis and pre-processing of microarray, next-generation sequencing, and genomic data, and is currently interested translational work, developing diagnostic tools and discovering biomarkers. Dr. Irizarry is one of the founders of the Bioconductor Project, an open source and open development software project for the analysis of genomic data.
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Statistical Inference and Modeling for High-throughput Experiments (edX)

A focus on the techniques commonly used to perform statistical inference on high throughput data. In this course you’ll learn various statistics topics including multiple testing problem, error rates, error rate controlling procedures, false discovery rates, q-values and exploratory data analysis. We then introduce statistical modeling and how it [...]

Statistics and R (edX)

An introduction to basic statistical concepts and R programming skills necessary for analyzing data in the life sciences. We will learn the basics of statistical inference in order to understand and compute p-values and confidence intervals, all while analyzing data with R. We provide R programming examples in a [...]

Case Studies in Functional Genomics (edX)

Perform RNA-Seq, ChIP-Seq, and DNA methylation data analyses, using open source software, including R and Bioconductor. We will explain how to perform the standard processing and normalization steps, starting with raw data, to get to the point where one can investigate relevant biological questions. [...]

Advanced Bioconductor (edX)

Learn advanced approaches to genomic visualization, reproducible analysis, data architecture, and exploration of cloud-scale consortium-generated genomic data. In this course, we begin with approaches to visualization of genome-scale data, and provide tools to build interactive graphical interfaces to speed discovery and interpretation. Using knitr and rmarkdown as basic authoring [...]

Introduction to Bioconductor (edX)

The structure, annotation, normalization, and interpretation of genome scale assays. We begin with an introduction to the biology, explaining what we measure and why. Then we focus on the two main measurement technologies: next generation sequencing and microarrays. We then move on to describing how raw data and experimental [...]

Introduction to Linear Models and Matrix Algebra (edX)

Learn to use R programming to apply linear models to analyze data in life sciences. Matrix Algebra underlies many of the current tools for experimental design and the analysis of high-dimensional data. In this introductory data analysis course, we will use matrix algebra to represent the linear models that [...]